Clinical Insight

Clinical Insight, a series of technical reports brought to you by ACM Global Central Lab, is written by our team of experts on issues effecting clinical testing today.  Based on their knowledge and experience with safety and specialty testing, our experts provide detailed information concerning current methodology, specimen requirements, and reference ranges on new and specialized tests. 

In Clinical Insight, our experts take it one step further to provide their opinions on the clinical significance of specific tests and how they can impact your clinical trial.

The Pathologist’s Role in the Diagnosis and Management of Disease
In the clinical trial arena, pathology plays a critical role when tissue specimens are an essential component for the diagnosis and for assessing response to treatment, especially in oncology studies. In many cases, the central laboratory provides the confirmation of diagnosis for valid inclusion of the subject in a trial. This issue provides the key elements for a successful study involving pathology tissue.

This issue focuses on LIMS (Laboratory Information Management Systems); what is it, how it has developed within the clinical trials industry and where the future possibilities lie in improving its functionality and integration with other processes. 

An Insight into the Role of an ACM Project Manager
Understand the relationship between the client and the Project manager, which allows improved communication and consistency across trials moving forward. 

Flow Cytometric Multiplexing: Multiple Analyte Detection System
The latest flow cytometer technology can detect and simultaneously measure up to 20 cytokines in a small sample volume. Using the same principles as ELISA, this report presents scenarios of the advantages of flow cytometric multiplexing.

The Use of Liquid-based Collection Methods for Women's Health Screening
This issue reports on the advantages of liquid-based collection methods for not only cervical cancer screening, but also for sexually transmitted diseases. Includes analysis on current HPV, Chlamydia and Neisseria Gonorrhoeae testing.

 

Understand Physiological Processes between Energy Metabolism and Appetite Regulation with Tests
With the worldwide rise of obesity and metabolic diseases, labs should conduct ongoing test monitoring to see what may be of value for obesity.  This report covers which tests are well-established and which provide beneficial results.

Nephrotoxicity Testing in Clinical Trials to Improve Patient Safety
This issue presents newer procedures for the evaluation of kidney function such as the Modification of Diet in Renal Disease (MDRD)2 equation and Cystatin C in the assessment of kidney function in non transplant patients.