Pharmacodynamic (PD) Biomarkers

ABS Laboratories has more than 20 years of experience providing bioanalytical services, data modeling, and drug stability studies through custom pharmacokinetic (PK) and pharmacodynamic (PD) assay development, transfer and validation.

  • GLP and GCP standards
  • Expertise in liquid chromatography combined with mass spectrometry (LC-MS/MS)
  • Direct line of communication with the lead scientist(s)
  • Develop and validate assays for multiple analytes
  • Develop stabilization procedures for hard-to-assay drugs in multiple matrices

R&D support on controlled drugs:

  • Novel formulations of cannabidiol (CBD): tetrahydrocannabinol (THC) to improve bioavailability PK support quantifying CBD, THC and 11-hydroxy THC in plasma samples
  • Novel acetyl morphine and morphine formulations
  • PK support with morphine, MAM, and the 3 and 6 glucuronides
  • Ketamine
  • Naloxone