Improvements in drug delivery and drug targeting methods have the potential to enhance the efficacy of a drug by decreasing degradation and loss. These novel systems may also minimize the impact of side-effects and increase the concentration of a drug at its intended site of action. Our chemists have participated in a number of studies designed to explore the utility of slow and quick drug delivery systems using the following types of pharmaceutical delivery systems:
A type of liposome that forms a single or multilayered phospholipid bilayer. The interior of a liposomal vesical encloses polar drug molecules, and with the appropriate biochemical modifications allows passive drug diffusion to the exterior of the vesicle.
A colloidal drug carrier system suspended in an aqueous solution and comprised of self-assembled amphiphilic block copolymers. The drug can be physically trapped within the micelles and transported at concentrations greater than their intrinsic water solubility.
A topical route of administration by which drugs held or applied in the buccal area (in the cheek) diffuses through the oral mucosa and enters directly into the bloodstream.
Applying drugs through the skin.
Administers drugs directly to the lungs.